Protective Effect of Previous SARS-CoV-2 Infection against Omicron BA.4 and BA.5 Subvariants

New England Journal of Medicine

This article shows that the protection of a previous COVID-19 infection against reinfection with a BA.4 or BA.5 subvariant was lower than that against reinfection with a BA.1 or BA.2 subvariant because of more waning of immune protection over time and a greater capacity for immune-system evasion with the BA.4 and BA.5 subvariants.

Journal Article